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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5ae31b10e30d6047f504c6eb49e700c9c48f74870f728995f21fccfd59d354' 
  AND token = '/ebv9ldtqu+/ei7hQj+P4ATzBEoJZ39Y/ivZpNNnaXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}