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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624b3c8897a55cbe38f61d5044e6fed7e265570e44e3a4ec45f752fe1e7269d3' 
  AND token = 'h6NSBBfZ/NFMM9D+5aTQINvt3Z0J9CH38lYRCp0WaUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}