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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cf89ca6566360a214cff78a68ecd6256d36f1dd03fc653f3432533e45a658da' 
  AND token = 'XT7ymX6Jo9oqXcyK/gvNL/U34OmlXvffXvUeMA6F8L4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}