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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23d806e66318d68e9708523d3589e1d29dbbf2bc0876d4060af82950cfd0b4a4' 
  AND token = 'emGXCyHkCDQMiZI0RI/koZC1rW1n7hjJ1RDuI/mqN6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}