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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf580ad16f2a76963080ec5860bd6af3bd059edded85d8f64e96c81b5d04e6cd' 
  AND token = 'RTEAHe4HFrf+uWyDhY2oruO6n49dsoIV/5oY05otSHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}