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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b2af48bfb4b17761faffeb1ef9fbdb5b7fec8eebdcf5f7b20312f3f075eb241' 
  AND token = '2wg6m+hIacF+81cGXnHkFCe015l4hMQoy8TWYsU7Ny0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}