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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f435759a2f68fb722a18d5a1d33a50d646796ae8c482222a897951f239fa8de3' 
  AND token = '1S+mg3E8Y/Kc2praTZKYNgPjboFMIC4HcdOZaEwqsDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}