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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d469ba10e50b9542aa4a8015da1d8fa3b985f151ccfe182c14bc50dbd65242f' 
  AND token = 'tMjON7+jh6/9gx5im9SiN86oerEegHbedBbrYN3kvmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}