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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d43752ec4645c1b1a56118d4c7356f91aa2e7c005452e867df3c22cf82cbe46' 
  AND token = 'AVkZuxud0Kz2IzyWS3rRHAZags+D1zmE2qur0LNS1Vc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}