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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eca6f49b061a44267e1b76ad06668fd15b09c9779fe56291b47836bb49b23d30' 
  AND token = 'D4GZ1Kc2u4iTx1HB8ifOBptbq32s1VWzJJgSS87y/HA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}