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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '133fd9f4853da3bda8ec05d31f6a5c3f01e1f7dd92d0563269f6b69c8823b29f' 
  AND token = 'YFwvl1uvpFkxNU8+ahjyc++5kuROT5mG9t+XJx4D0bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}