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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '107bf3d0f2d23a58db6a9e8e4a20f052363e19b209191c02799523f444e8ab64' 
  AND token = '8UXo7hG2ERb4SfZ5S8eypL6RjgSgP0uD/Jkf4Kqihz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}