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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f06c7e80b326133e682231fca2619db5bf6642e8ff14079da7519e3ed4c14a29' 
  AND token = 'nSu1Fd1ZXe8+JxFUNmONXh9oyShmndkkIWNsNqMDTkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}