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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afb4b2ef17d62ffcfd589bd4f8205b790fff9ff25d8780c03edb17094de2ddb3' 
  AND token = 'Lj0eW3RIPT0E3PwS9uNgchvsevdKw5A9ceQjWhIHA9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}