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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0274e3bdc189309f523a1cfead50a3184f1fe2c799ab00ca4f5ee0743140dfa3' 
  AND token = 's72ejv+bLsHHReiBz9qROdwuPING9vdKSywc1y1nhUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}