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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceb8aa815b5488e2db23b202575ab84ea379532c3f643c24147ba8c386a6e7ce' 
  AND token = 'HZzE8u2MiKZANY1OA4Z58faVXQgvlpRKtpyLxJwMgI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}