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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21325410ae2ae498be257fa73327ca0e9b8133f08011dd482955686af8dcc183' 
  AND token = 'C+2AVtYukN46u2qqb6PKLFAIazOmy2IRoO5d2/6gZvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}