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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c62e04d5b855bd0c9113d4c8e1b64207e0fa6e361b6bab16720a291bda212184' 
  AND token = 'mNX0FOX0Ayc0F0nzjw0un9JRtOg2wN8SMPjUKoJdqpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}