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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37b5a900d91840196d67438029a706f43c97a69e725101e98f09fc4a42527e6e' 
  AND token = 'pM+Sp7y9igG+FLr3t1E/t9kBw0JyFsBNv0/PcCIX3z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}