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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4417eb21b3c5d83c916f2aaf80ca74abe2149033cfb32136f23ecf221c75a9a5' 
  AND token = 'XDY+4oS2WoWo8aL8euAylbssqNSjiAQ4fbX1Q+TsXkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}