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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3049038e68664621e2fac01d04305880a7b1d8dbcafa60c7d536c03cc5fb02d3' 
  AND token = 'jkEYvA4aLpyzVsSyUkKrxusm1hfOpGdcjjP6/A+sryk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}