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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de12bdc8dfa4ff1fd220be7f6654ffe2b56c8360dbe8e385c1533491d75e4b26' 
  AND token = '7T1T7GpP7QdrpvzZ6b3d7XODtbFpc01jzupyx/Sl1TQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}