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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3d256061a8610a684dbebf44a3337212e78b8879eb7febe2f96ca34ec8c010e' 
  AND token = 'kDLzACfT4Af2Mcm2cDjZiLWNyJZmso7qnEPnVktYFME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}