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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e527e2c0bfb0b82da92bc2e1daf5db974cd480c26fa3b770d6f179ba979dfc38' 
  AND token = 'KyAx3/AcQ+zi7j2TBJniuqNdsIEZLdpUj6THrjMWBMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}