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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd389879181091c6caff5bc7048f1bbed415ca6963945e63638290729021c3992' 
  AND token = 'iNt/iL07s1TRmr08V3Rh1p6+Hv9y+yBavXfs5GcC4EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}