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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af2c6060cb9613c4f3aaad6a3685cb86819bc00785f23f3aba156ad94a5b47e0' 
  AND token = 'vp6KLe/K9YTAZtxFWXiS5qLURgj3dYM73BKA0DXIdGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}