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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e5400211fa27d6c8ce4d0834090b96cbdb54de8050e1e61dc9bb46a4b4d262' 
  AND token = 'aREMwLzYVS7RfJwQgpFHh+BQ05hSbHCd0S9yRmfLAVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}