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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da218779c25c51ad4139034e771cb167e4c3e6ece0cfc59f32d70ce2c5ec4612' 
  AND token = '3CI0xPJ4OPNuJSxEc8WRKa+9qUhMnXQryN1hlXbWGx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}