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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a556ca10e8cb5e3653d54245852be3e900c2c8e4b87cff2accb3f182f9aa866' 
  AND token = 'QxKKPGkjBZ4edcsF+Jbe7hKAeJdUomQ+pTFF+WkpHHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00208

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}