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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0a3fc886eca877c96ccdec86e75d758b4ec5384e6e8024da0c798c9a803031' 
  AND token = 'MiPjdEXVY0Rmidd5waU7V6UW6nREVR7OpubvSsSo8Gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00206

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}