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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e0d84271dd2dcd3ecab43c8e5528d022eb8c42e1e950705aa0a922057d3734' 
  AND token = 'w5NpIabM0k2lbETycMmmwh7jOE4J5TkcnVZ9RT0ZTgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}