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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13432d3e0d007a48348f5e61c96778c326c52821e2fb46eb84f178acc2dd6b71' 
  AND token = 'TWel3xWGhvhjVsPyvHEPmKAVVgb4OPE8JGsT5FfA4dQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}