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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e52a023f96870ca551d2b9a492f9a324f1d4a268b5e2a024529088cde0e4d52' 
  AND token = 'CtEzSmEh7nWWx+9JRmSkMKfRMnAD7Dt1BuLKGDKM/DU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}