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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67396efaf3364f9a96588ec71b4639f07e77b700dc817a779c4dc3ba3f6961c2' 
  AND token = '12u3Rf3LpEmVjJ57P5hC/EU2cUOdwu6t5DcBxrYuOgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00162

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}