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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40a2ae6e593b309f39e50d27cf1012df4435a35291af2adbf1a9983417afc86' 
  AND token = 'YUFV9WC8Az9dXb0NR23Mlq9PRRpSrrmA0d+EE0SxZls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}