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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a0be36056cba570e937bf53459a27a405d26c413b0cb5a2c5802ad085f0148' 
  AND token = 'H21HoUswZ1JQlthq3eqO+Q5xO94QFhtOKbgNaXaPuR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}