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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a11ce2201235228ad38ddbb1cbdaa4ff16ee97661dee96a4cae67fac09c62b9' 
  AND token = 'Sb12zQPh2BjpUBf/RYFRB/8nVpMnLhMLD5YuX8YzQuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}