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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44d6fbe4874bca3bb8a009e416463a20062d8c561b5155a13af9d541aca0f963' 
  AND token = 'hMesc/SqU3I+PiMaJTN70+6/WjGZjDMguu6JgRhcPQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}