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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b487070bbf81a416d058cf705316bd99dc8544b3ed65f2490dd0e0dd6f78198' 
  AND token = '5U25OoUE0OroC55bFx09WOj7zuYUYXo5UtFB0wadY+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}