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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d2d34800aa9b4b80f71ed694e8498186b26bb380b4b97322e4a3a2058f3d7d2' 
  AND token = 'Bq0c9hfPL81XVsBW3oKTJbPR5YuPmxXDx2j0fg2TiYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}