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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287fb7a0eb725d0f958171e2855b104e85756b763b9c26ac885ae8024f9a771e' 
  AND token = 't0gxpX35qeLnMMtnuebUuryDq9At8WZS/FBCIhjAnkw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}