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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e81affd52d7dcffef7f16fa4abdc2fb44d1bb1a42a11c5cfde338e89967c19f' 
  AND token = 'BgCbu6QjKX0Hil6+msjlx4I2H9yT8Wf9lzqBSXM3fUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}