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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '605a5e35a84de4385cbdfc2da81edca65696757e0546c809d993169e4b11dc14' 
  AND token = 'Mzv+ICIvjJUHdxUpKtb9Gm7u9UtYAR6Chdm1c1H+LMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}