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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7821d7761488da6e1a54ad245c3a194311054c1b2aec647c7f670a748b09b712' 
  AND token = 'kR6YF4ooeR6k/8xKWcr8eqreFXuUBrQbuYez/lJ+HIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}