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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae76a97639bfbcb07660bcfbb2749095dced28f26f5a340b2359eec5f76d186f' 
  AND token = 'R7Wu9WU8XMlbBdCYG+Yd1SNiMuP8Kj0/ZJ8aSUaXORc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}