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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae2f244756f1a8f049e3ca6dc4ead47709ec21d3b61601379f1fbaec8d1e27a6' 
  AND token = '583Zn6dG0pvyoRiy6kqBDB+k8kfJ7scWgyySDgvZjUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}