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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0df1cff9c8ec9b947d54be8d0d78e1df645d0c0a86887f18e04307b9ad5b3b' 
  AND token = 'IT1raYEng8JTrVohe+uQz8Cgb7myjObs7Ceh8Zjf8HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}