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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fb331cb3a2c99e1331fc6ce1f5acaacd5a269fd2b2b35a94951b5198312343' 
  AND token = 'GPo5G2DsTr5xXYHzlYcg1ID4rLI9DxGe1QOi7j7wW4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}