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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f33f2e035477e8972e357b5c97a579336df5c66e7a1ae645f02d010bbc63bd8' 
  AND token = 'PnHfcRJ7U1/5524Z34yx5Z/h+hD5jzH8p/QviT72PKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}