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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '412a84adf5c1d00d23320eea03dacbd81c752346de9c1029933520207fa40828' 
  AND token = 'gMWiZ3acDrezNlHtmxyRsLBCc9WN5QZBAiDTJigIqiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}